Antigen Processing

T cell recognition of antigen presenting cells depends on their expression of a spectrum of peptides bound to Major Histocompatibility Complex class I (MHC-I) and class II (MHC-II) molecules. Conversion of antigens from pathogens or transformed cells into MHC-I and MHC-II-bound peptides is critical for mounting protective T cell responses, and similar processing of self-proteins is necessary to establish and maintain tolerance.

  • Peptide binding to MHC molecules
  • Peptide binding to MHC molecules
  • Proteolysis and endocytic pathway
  • Human platelet antigen genotyping
  • Antigen processing generates antigenic peptides
  • The interaction of T cells with macrophages

Antigen Processing Conference Speakers

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