Histocompatibility Transplantation

The transplant of organs is one of the greatest therapeutic achievements of the twentieth century. In organ transplantation, the adaptive immunity is considered the main response exerted to the transplanted tissue, since the principal target of the immune response is the MHC (major histocompatibility complex) molecules expressed on the surface of donor cells. However, we should not forget that the innate and adaptive immunities are closely interrelated and should be viewed as complementary and cooperating.

  • Organ transplantation and adaptive immunity
  • Therapeutic transplantations
  • Innate and adaptive immunities
  • Immunoglobulin receptors
  • Cytokines and chemokines

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